Homocysteine
Amino-acid metabolite tied to B-vitamin status, vascular health, and methylation efficiency.
Blood draw
48 hrs
Physician-reviewed
What this panel measures
- Total homocysteine — an amino-acid metabolite in the methylation pathway
- Indirectly reflects folate, B12, and B6 status
Why providers order it
- Cardiovascular and stroke risk assessment
- Evaluating B-vitamin status and methylation efficiency
- Workups for early heart or vascular disease with no classic risk factors
- Cognitive-health and healthy-aging panels
Fasting overnight is recommended for the most reliable value.
Homocysteine: frequently asked questions
What does high homocysteine mean?
Elevated homocysteine usually points to low folate, B12, or B6 — the vitamins that clear it from the blood. Persistently high levels are associated with damage to artery linings over time and are often correctable with supplementation your provider directs.
Should I fast before a homocysteine test?
Yes — an overnight fast is recommended before the draw.
How long do homocysteine results take?
Results are typically reported within 48 hours and physician-reviewed before release.
Often ordered together
Advanced Lipid Panel + ApoB
Beyond standard cholesterol: particle counts and ApoB for true cardiovascular risk stratification.
High-Sensitivity CRP
Low-grade vascular inflammation marker that refines cardiovascular risk beyond lipids alone.
Micronutrient Panel
Vitamin D, B12, folate, iron, ferritin, zinc, and magnesium — the cellular fuel gauge.
This page is educational and does not replace medical advice. Testing decisions should be reviewed with a licensed provider.