Celiac & Gluten Sensitivity
Celiac serology with total IgA to rule out false negatives, plus gluten sensitivity markers.
Blood draw
48 hrs
Physician-reviewed
What this panel measures
- tTG-IgA — the first-line celiac antibody
- Total IgA — rules out IgA deficiency, which causes false negatives
- Deamidated gliadin IgG — an additional sensitivity marker
Why providers order it
- Chronic diarrhea, bloating, or unexplained weight loss
- Unexplained anemia or nutrient deficiencies
- Family history of celiac disease or autoimmune conditions
- Skin rash (dermatitis herpetiformis) or persistent mouth ulcers
Keep eating gluten before testing. Antibodies only appear in response to ongoing gluten exposure — going gluten-free beforehand can produce a falsely negative result.
Celiac & Gluten Sensitivity: frequently asked questions
Do I need to eat gluten before a celiac test?
Yes — keep a normal, gluten-containing diet for several weeks before the draw. Testing after going gluten-free frequently reads negative even in people with celiac disease.
What does total IgA add?
About 1 in 40 people with celiac disease cannot make IgA antibodies at all, so the standard tTG-IgA test looks negative despite active disease. Measuring total IgA catches this and lets the lab interpret the panel correctly.
How long do results take?
Celiac serology results are typically reported within 48 hours and physician-reviewed before release.
Often ordered together
Comprehensive Stool Analysis
Microbiome mapping, digestion markers, inflammation, and pathogen detection in one panel.
Complete Blood Count + Differential
Red cells, white cells, and platelets to screen for anemia, infection, and immune response.
This page is educational and does not replace medical advice. Testing decisions should be reviewed with a licensed provider.